Synthesis of Diverse Azolo [c] quinazolines by Palladium (II)??Catalyzed Aerobic Oxidative Insertion of Isocyanides

T Vlaar, L Bensch, J Kraakman…

文献索引：Vlaar, Tjostil; Bensch, Lisa; Kraakman, Jasper; Vande Velde, Christophe M. L.; Maes, Bert U. W.; Orru, Romano V. A.; Ruijter, Eelco Advanced Synthesis and Catalysis, 2014 , vol. 356, # 6 p. 1205 - 1209

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被引用次数: 8

摘要

Abstract: We report the palladium (II)-catalyzed aerobic oxidative coupling of isocyanides with various (2-aminophenyl) azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo [c] quinazolines was obtained by this new approach. Keywords: homogenous catalysis; isocyanides; oxidation; palladium; quinazolines