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Synthesis of the phenylpyridal scaffold as a helical peptide mimetic

…, DJ Kuster, GR Marshall

文献索引:Bourne, Gregory T.; Kuster, Daniel J.; Marshall, Garland R. Chemistry - A European Journal, 2010 , vol. 16, # 28 p. 8439 - 8445

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被引用次数: 15

摘要

Abstract Phenylpyridal-and phenyldipyridal-based scaffolds have been designed and synthesized as novel helical peptide mimetics. The synthesis required optimisation and selective alkylation in producing 2, 6-functionalized 3-hydroxypyridine derivatives for a ...