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Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ 2) selective ligands

ME Ashford, VH Nguyen, I Greguric, TQ Pham…

文献索引:Organic and Biomolecular Chemistry, , vol. 12, # 5 p. 783 - 794

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被引用次数: 4

摘要

... 61, OMe, H, 2, 4.31, 4.4 ± 1.3, 76 ± 16, 17.3. 62, H, OMe, 1, 4.33, 35 ± 5.3, 616 ± 12, 17.6. ... Experimental. Chemistry – general considerations. ... NaHCO 3 (25 mL), brine (25 mL) and H 2 O (20 mL). The organic layers were combined, dried (Na 2 SO 4 ) and the organic solvent removed ...