The Synthesis of Enantiopure ω??Methanoprolines and ω??Methanopipecolic Acids by a Novel Cyclopropanation Reaction: The “Flattering” of Proline

S Hanessian, U Reinhold…

文献索引：Hanessian, Stephen; Reinhold, Ulrich; Gentile, Gabriella Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 17 p. 1881 - 1884

全文：HTML全文

被引用次数: 57

摘要

Proline occupies a prominent position in the hierarchy of natural amino acid constituents of mammalian proteins.“As part of a peptidic motif, its unique structure results in secondary amide bonds, leading to important conformational and functional consequences.[21 For ...