Xenobiotica

Metabolism and pharmacokinetics of dihydrocodeine in dog

M Konishi, Y Shiono, M Ohno, H Takahashi, T Aoki

文献索引：Konishi; Shiono; Ohno; Takahashi; Aoki Xenobiotica, 1994 , vol. 24, # 7 p. 591 - 601

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被引用次数: 3

摘要

1. The metabolism and pharmacokinetics of dihydrocodeine have been studied in dog. Urinary metabolites after oral administration of dihydrocodeine were identified using hplc with diode-array and ms. 2. In urine, dihydronorcodeine, dihydromorphine and dihydrocodeine glucuronide were identified in comparison with their authentic standards, and dihydronorcodeine 6-glucuronide also appeared to be excreted as a metabolite. 3. ...