Furan ring opening–pyrrole ring closure. A simple route to 1, 2, 3, 4-tetrahydropyrrolo [1, 2-a] pyrazin-3-ones

…, TA Nevolina, VA Shcherbinin, LN Sorotskaya…

文献索引：Trushkov, Igor V.; Nevolina, Tatyana A.; Shcherbinin, Vitaly A.; Sorotskaya, Lyudmila N.; Butin, Alexander V. Tetrahedron Letters, 2013 , vol. 54, # 30 p. 3974 - 3976

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被引用次数: 12

摘要

Pyrrole derivatives represent a very important class of heterocyclic compounds. 1 Among them, pyrroles annulated to other heterocycles via a C–N bond can be highlighted due to the broad spectrum of their bioactivity. The antitumor and antibiotic agent, mitomycin is a pyrrolo[1,2-a]indole derivative, whilst the anti-HIV agent castanospermine has an indolizidine scaffold; Erythrina alkaloids belong to pyrrolo[2,1-a]isoquinoline family; and the ...