Synlett

Sequential Aza-Claisen rearrangement and ring-closing metathesis as a route to 1-benzazepine derivatives

D Ghosh, L Thander, SK Ghosh, SK Chattopadhyay

文献索引：Ghosh, Debalina; Thander, Latibuddin; Ghosh, Sanjay K.; Chattopadhyay, Shital K. Synlett, 2008 , # 19 p. 3011 - 3015

全文：HTML全文

被引用次数: 7

摘要

The thermal rearrangement of N-allylanilines require drastic conditions compared to corresponding aryl allyl ethers. [¹5] However, such rearrangements usually proceed with significant rate enhancement under protic or Lewis acid catalysis. [¹6] It has further been observed that the presence of an additional N-alkyl group in the N-allylaniline moiety greatly enhances the rate of an aromatic aza-Claisen rearrangement. [¹7] This led us to consider selective monorearrangement of ...