Journal of medicinal chemistry

Fluorene derivatives for antitumor activity

KC Agrawal

文献索引：Agrawal,K.C. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 99 - 101

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被引用次数: 8

摘要

(V) and dimethyl 2, 7-fluorenedisulfonate (TII), were prepared for arititunior screening. I1 ethanesulforiyl esters have been reported2 to be active cancer chemotheraputic agents. Busulfan, 1, 4-di (methanesulfonyloxy)-butane, is a well-known representative of this type of alkylating agent. In order to determine if replacement of the alkane chain of four carbon atoms by a ring system such as fluorene would produce compounds with antineoplastic ...