Microwave promoted one-pot synthesis of 2-aryl substituted 1, 3, 4-oxadiazoles and 1, 2, 4-oxadiazole derivatives using Al 3+-K10 clay as a heterogeneous catalyst
Abstract An efficient, inexpensive method is developed for the one-pot synthesis of 2-aryl substituted 1, 3, 4-oxadiazoles and 1, 2, 4-oxadiazoles starting from acid hydrazides and trimethyl orthoformate under solvent-free, microwave conditions using a reusable Al 3+-K10 montmorillonite clay as a heterogeneous catalyst. The novelty of the present study lies in the synthesis of oxadiazole and benzimidazole moieties in a one-pot process in high yield ...
