On the synthesis of 5??ethyl meldrum's acid

…, H El??Hafidi, B Rigo, D Couturier

文献索引：Akue-Gedu, Rufine; El-Hafidi, Hayate; Rigo, Benoit; Couturier, Daniel Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 2 p. 365 - 369

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被引用次数: 2

摘要

Reductive alkylation of Meldrum's acid with acetaldehyde can give, depending on the experimental conditions, either a new dimer (5-[3-(2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-yl) butyl]-2, 2-dimethyl-1, 3-dioxane-4, 6-dione) or ethyl Meldrum's acid (2, 2-dimethyl-1, 3- dioxane-4, 6-dione). A best way to obtain this latter product is synthesis of 1- ethoxyethylidene Meldrum's acid from reaction of Meldrum's acid with triethyl orthoacetate, ...