Leonurine-cysteine analog conjugates as a new class of multifunctional anti-myocardial ischemia agent

C Liu, W Guo, X Shi, MA Kaium, X Gu, YZ Zhu

文献索引：Liu, Chunhua; Guo, Wei; Shi, Xueru; Kaium; Gu, Xianfeng; Zhu, Yi Zhun European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 3996 - 4009

全文：HTML全文

被引用次数: 17

摘要

The design, synthesis and biological evaluation of novel Leonurine-cysteine analog conjugates 3, 5-dimethoxy-4-(2-amino-3-prop-2-ynylsulfanyl-propionyl)-benzoic acid 4- guanidino-butyl ester (1a), 3, 5-dimethoxy-4-(2-animo-3-allysulfanyl-propionyl)-benzoic acid 4-guanidino-butyl ester (1b) and 3, 5-dimethoxy-4-(3-(2-chlorocarbonyl-ethyldisulfanyl)- propionyl)-benzoic acid 4-guanidino-butyl ester (2) were reported in this paper. We tested ...