2-Substituted aminopyrido [2, 3-d] pyrimidin-7 (8 H)-ones. Structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity

SR Klutchko, JM Hamby, DH Boschelli…

文献索引：Journal of Medicinal Chemistry, , vol. 41, # 17 p. 3276 - 3292

被引用次数: 150

摘要

... Journal of Medicinal Chemistry. ... Departments of Chemistry, Cancer Research, Vascular and Cardiac Diseases, and Pharmacokinetics and Drug Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor ...

17759-30-7

(4-甲基氨基-2-甲烷磺酰基...

Application of β-(2-Chloroaroyl) thioacetanilide in Synthesi...

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2-Substituted aminopyrido [2, 3-d] pyrimidin-7 (8 H)-ones. S...

[Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292]

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