Tetrahedron letters

Synthesis of bivalent ligands of β-carboline-3-carboxylates via a palladium-catalyzed homocoupling process

W Yin, PVVS Sarma, J Ma, D Han, JL Chen, JM Cook

文献索引：Yin, Wenyuan; Sarma, P. V. V. Srirama; Ma, Jun; Han, Dongmei; Chen, Jessica L.; Cook, James M. Tetrahedron Letters, 2005 , vol. 46, # 37 p. 6363 - 6368

全文：HTML全文

被引用次数: 18

摘要

The first synthesis of bivalent ligands of β-carboline-3-carboxylates has been achieved from β-carboline-3-carboxylate tert-butyl ester (βCCt) via Sonogashira and palladium-catalyzed homocoupling processes. The Boc protected intermediate, an iodo-β-carboline-3- carboxylate, was employed to provide a general entry into a series of bivalent ligands structurally similar to βCCt.