Synthesis

The reaction of arylacetones with boron tribromide

R Dupont, P Cotelle

文献索引：Dupont, Romain; Cotelle, Philippe Synthesis, 1999 , # 9 p. 1651 - 1655

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被引用次数: 5

摘要

Abstract: Treatment of arylacetones 1 with boron tribromide gives 1, 3-dimethyl-2- arylnaphthalenes 3 in fair to good yields by a tandem aldol condensation-intramolecular cyclization. This reaction is limited to the electron-rich arylacetones. In the case of methoxyphenylacetones, a demethylation occurs leading to 1, 3-dimethyl-2- hydroxyphenylnaphthols. Other cyclization may occur for orthomethoxyphenylacetones ...