New synthetic route to pharmacologically active 1-(N, N-dialkylamino)-3, 3-diarylpropanes via rhodium-catalyzed hydroformylation of 1, 1-diarylethenes

…, L Cazzolato, M Marchetti, S Paganelli

文献索引：Botteghi; Cazzolato; Marchetti; Paganelli Journal of Organic Chemistry, 1995 , vol. 60, # 20 p. 6612 - 6615

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被引用次数: 58

摘要

The rhodium-catalyzed hydroformylation of olefins containing various functions is a useful tool for the preparation of numerous compounds having biological However, there are several problems connected with the use of nonconventional olefin substrates; in particular, the lack of sufficiently high chemo-and regioselectivity represents in several instances a strong limitation to make hydroformylation attractive for industrial appli~ ation.~