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Aryloxyalkylaminoguanidines. Their Synthesis and Biological Properties

J Augstein, SM Green, AM Monro…

文献索引:Augstein,J. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 391 - 400

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被引用次数: 22

摘要

Proton magnetic resonance has been iised to show that the productr of guanylation of aryloxyethylhydraziiieq are (aryloxyethy1amino) giianidines. Several such aminoguanidines containing chlorine and methyl substitiieiits in the aromatic ring have been showli 1 o possebs adrenergic nc1iron blocking properties ant1 to inhihit dopamine 6'-oxidase in vitTo.