The use of glycosides of 6-and 8-acylamino-4-methylumbelliferone in studies of the specificity and properties of human lysosomal glycolipid hydrolases

…, IK Kozlova, GS Ilyina, MA Mikhaylova, EM Beyer

文献索引：Wiederschain, German Ya.; Kozlova, Inna K.; Ilyina, Galina S.; Mikhaylova, Margarita A.; Beyer, Elena M. Carbohydrate Research, 1992 , vol. 224, p. 255 - 272

全文：HTML全文

被引用次数: 14

摘要

Abstract A series of 6-and 8-acylamino-4-methylumbelliferyl β-d-galactopyranosides, β-d- glucopyranosides, and α-l-fucopyranosides having various fatty acid residues were synthesized; 6-(9) and 8-hexadecanoylamino-4-methylumbelliferyl β-d-galactopyranoside (10) were shown to be substrates for human galactocerebrosidase. Analogs of 9 with shorter acyl residues (octanoyl and butanoyl) were substrates for another type of β-d- ...