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Tetrahedron: Asymmetry

Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline

M Amedjkouh, P Ahlberg

文献索引:Amedjkouh, Mohamed; Ahlberg, Per Tetrahedron Asymmetry, 2002 , vol. 13, # 20 p. 2229 - 2234

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被引用次数: 46

摘要

Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R, 5S)-2-trichloromethyl-1-aza-3- oxabicyclo-[3.3. 0]-octan-4, 8-dione 3 and its enantiomer are readily available by reaction of