Tetrahedron

Microwave-mediated 'click-chemistry'synthesis of glycoporphyrin derivatives and in vitro photocytotoxicity for application in photodynamic therapy

…, D Naud-Martin, D Carrez, A Croisy, P Maillard

文献索引：Garcia, Guillaume; Naud-Martin, Delphine; Carrez, Daniele; Croisy, Alain; Maillard, Philippe Tetrahedron, 2011 , vol. 67, # 26 p. 4924 - 4932

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被引用次数: 40

摘要

Abstract In this paper, we report the synthesis of a series of porphyrins, designed as photodynamic therapy (PDT) agents, substituted by three glycosyl units linked by a triazole group to chromophore in the aim to target tumor cells overexpressing lectin-type membrane receptors, by 'click-chemistry'under microwave heating.