Tetrahedron

Chiral synthesis VIA organoboranes. 26. An efficient synthesis of isoprenyl derivatives of borane-valuable reagents for the isoprenylboration of aldehydes. A …

HC Brown, RS Randad

文献索引：Brown, Herbert C.; Randad, Ramnarayan S. Tetrahedron, 1990 , vol. 46, # 13-14 p. 4463 - 4472

全文：HTML全文

被引用次数: 44

摘要

Preparation of B-isoprenyldialkylboranes is achieved by adopting the Brandsma modification of the Schlosser procedure, namely metallation of isoprene with potassium 2, 2, 5, 5-tetramethylpiperidide followed by sequential treatment with B-methoxydialkylborane and boron trifluoride-etherate. These reagents are used for the convenient isoprenylation of aldehydes. Reaction of isovaleraldehyde and β, β-dimethylacrolein with B2' ...