Synthesis of novel benzoxaborole-containing phenylalanine analogues

…, JJ Plattner, V Hernandez, CZ Ding, W Wu, Y Yang…

文献索引：Li, Xianfeng; Plattner, Jacob J.; Hernandez, Vincent; Ding, Charles Z.; Wu, Wei; Yang, Yang; Xu, Musheng Tetrahedron Letters, 2011 , vol. 52, # 38 p. 4924 - 4926

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被引用次数: 13

摘要

Abstract The synthesis of novel benzoxaborole-containing phenylalanine analogues 2 and 3 has been developed. The key steps involve the preparation of appropriate precursors from the readily available amino acids and the formation of benzoxaborole ring directly in the corresponding amino acid fragment. The resulting compounds 2–3 show improved water solubility at physiological pH, suggesting their potential use as boron delivery agents for ...