Tetrahedron Letters

Enantioselective synthesis of siloxycyclopropanes and of???-oxocarboxylates by asymmetric catalysis

T Kunz, HU Reissig

文献索引：Kunz, Thomas; Reissig, Hans-Ulrich Tetrahedron Letters, 1989 , vol. 30, # 16 p. 2079 - 2082

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被引用次数: 24

摘要

Abstract Up to 48% enantiomeric excess have been attained by cyclopropanation of silyl enol ethers with methyl diazoacetate in the presence of optically active Cu-catalysts. Subsequent ring opening of resulting siloxycylopropanes gives???-oxocarboxylates with a maximum enantiomeric excess of 37%.