Stereochemistry of reactions of the inhibitor/substrates L-and D-β-chloroalanine with β-mercaptoethanol catalysed by L-aspartate aminotransferase and D-amino acid …
B Adams, K Lowpetch, F Thorndycroft…
文献索引：Adams, Benjamin; Lowpetch, Kreingkrai; Thorndycroft, Faye; Whyte, Sheena M.; Young, Douglas W. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 18 p. 3357 - 3364
Two members of the α-family of PLP-dependent enzymes, L-aspartate aminotransferase and D-amino acid aminotransferase, have been shown to catalyse β-substitution of L-and D-β- chloroalanine respectively with β-mercaptoethanol, reactions typical of the β-family of PLP- dependent enzymes. The reaction catalysed by L-aspartate aminotransferase has been shown to occur with retention of stereochemistry, a typical outcome for reactions catalysed ...
