Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists

J Cluzeau, S Oishi, H Ohno, Z Wang, B Evans…

文献索引：Organic and Biomolecular Chemistry, , vol. 5, # 12 p. 1915 - 1923

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被引用次数: 28

摘要

... The majority of the NMR signals were well resolved at distinct chemical shifts for product 39. ... with triethylamine (20.8 ml, 2 eq.) and TIPSCl (19.1 ml, 1.2 eq.) and stirred for 5 h at ... The reaction was partitioned between ether and HCl 0.5 M. The organic layer was washed twice with ...