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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N- …

N Nishimura, MH Norman, L Liu, KC Yang…

文献索引:Journal of Medicinal Chemistry, , vol. 57, # 7 p. 3094 - 3116

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被引用次数: 15

摘要

... Journal of Medicinal ... Department of Therapeutic Discovery—Medicinal Chemistry, ‡ Department of ... Despite many years of efforts to effectively manage diabetes, there is still a great unmet medical need for orally available, safe, and effective drugs for the treatment of diabetes.(2 ...