Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

M Catto, L Pisani, F Leonetti, O Nicolotti…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 21, # 1 p. 146 - 152

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被引用次数: 42

摘要

... Bioorganic & Medicinal Chemistry. ... and academic scientists, the pathophysiological events causing the onset and progression of AD remain obscure and, as a consequence, the setup of appropriate pharmacological, disease-modifying therapies are still an unmet medical need ...