Concise Synthesis and X-Ray Crystal Structure of N-Benzyl-2-(pyrimidin-4′-ylamino)-thiazole-4-carboxamide (Thiazovivin), a Small-Molecule Tool for Stem Cell …
…, M Granitzka, D Stalke, C Ducho
文献索引:Ries, Oliver; Granitzka, Markus; Stalke, Dietmar; Ducho, Christian Synthetic Communications, 2013 , vol. 43, # 21 p. 2876 - 2882
Stem cell research is one of the most promising fields of modern biomedical research and regenerative medicine. Limited availability and ethical concerns suggest the renouncement of embryonic stem cells (ESCs), thus raising the need for more efficient procedures for the generation of stem cells, ideally through reprogramming of mammalian cells. The small molecule N-benzyl-2-(pyrimidin -4′-ylamino)-thiazole-4-carboxamide (thiazovivin) is known to improve the generation of ...