Tetrahedron

Novel 6-substituted benzothiazol-2-yl indolo [1, 2-c] quinazolines and benzimidazo [1, 2-c] quinazolines

S Frère, V Thiéry, C Bailly, T Besson

文献索引：Frere, Stephane; Thiery, Valerie; Bailly, Christian; Besson, Thierry Tetrahedron, 2003 , vol. 59, # 6 p. 773 - 779

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被引用次数: 52

摘要

The synthetic route to and a preliminary biological evaluation of novel indolo [1, 2-c] quinazolines (8) and benzimidazo [1, 2-c] quinazolines (9) are described. The products were obtained by condensation of the appropriate diamines (eg 2-(2-aminophenyl) indole or 2-(2- aminophenyl) benzimidazole) with 2-cyanobenzothiazoles. This work further demonstrates the general applicability of microwaves for a facile and rapid access to original ...