Tetrahedron Letters

Synthesis of biphenyl-based phosphines by Suzuki coupling

C Baillie, W Chen, J Xiao

文献索引：Baillie, Colin; Chen, Weiping; Xiao, Jianliang Tetrahedron Letters, 2001 , vol. 42, # 51 p. 9085 - 9088

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被引用次数: 33

摘要

A series of phosphine oxides has been synthesised by the palladium-catalysed Suzuki coupling of arylboronic acids with OPPh2 (o-C6H4Br). On reduction with trichlorosilane, functionalised, biphenyl-based phosphine ligands were obtained in good yields. Our preliminary results indicate these ligands to be effective for palladium-catalysed C–C coupling reactions including the formation of their own oxides.