Tetrahedron

Copper catalyzed conjugate addition of highly functionalized arylmagnesium compounds to enones

G Varchi, A Ricci, G Cahiez, P Knochel

文献索引：Varchi, Greta; Ricci, Alfredo; Cahiez, Gerard; Knochel, Paul Tetrahedron, 2000 , vol. 56, # 18 p. 2727 - 2731

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被引用次数: 34

摘要

Highly functionalized arylmagnesium bromides are readily prepared by an iodine– magnesium exchange reaction. In the presence of catalytic amounts of copper (I) salts and chlorotrimethylsilane, they add to various enones leading to the conjugate addition products in 66–89% yield.