Synthesis, photochemical E (trans)→ Z (cis) isomerization and antimicrobial activity of 2-chloro-5-methylpyridine-3-olefin derivatives
B Gangadasu, MJR Reddy, M Ravinder…
文献索引：Gangadasu; Reddy, M. Janaki Ram; Ravinder; Kumar, S. Bharat; Raju, B. China; Kumar, K. Pranay; Murthy; Rao, V. Jayathirtha European Journal of Medicinal Chemistry, 2009 , vol. 44, # 11 p. 4661 - 4667
2-Chloro-5-methylpyridine-3-olefin derivatives (3a-e) have been synthesized from 2-chloro- 5-methylnicotinaldehyde (1) and studied their photochemical E (trans)→ Z (cis) isomerization upon direct irradiation and triplet sensitized excitation for the first time. The triplet sensitized excitations of the compounds yielded high Z (4a–e) isomer composition, whereas the direct excitation results in less Z (4a–e) isomer composition, indicating triplet ...
