Abstract:~-Acety1-N1-(4-fluorobenzyl) carbazoy1-a-chymotrypin is a catalytically inactive protein which should closely resemble the acylated enzyme intermediate formed during reaction of chymotrypsin with substrates derived from phenylalanine. Fluorine and deuterium nuclear relaxation in this carbazoylated enzyme and a specifically deuterated analogue have been examined. Analysis of the spin-lattice relaxation data (observed at ...
