Various 1-[l-[2-[3-(alkylamino)-2-hydroxypropoxy] phenyl] vinyl]-1H-azoles were synthesized and investigated for 0-adrenoceptor-blocking and antiarrhythmic activities. Although no compounds showed more potent@-blocking effects than propranolol in the isolated guinea pig right atria, many compounds exhibited significant antiarrhythmic effects against aconitine or ischemic arrhythmia in mice or dogs. 1-[2, 5-Dichloro-6-[1-(1H-imidazol-1-y1)- ...
![[2S]-O-isopropylidene-3-isopropylamino-1,2-propanediol结构式](https://image.chemsrc.com/caspic/259/68430-26-2.png)
