Design of Potent IGF1??R Inhibitors Related to Bis??azaindoles

C Nemecek, WA Metz, S Wentzler…

文献索引：Chemical Biology and Drug Design, , vol. 76, # 2 p. 100 - 106

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被引用次数: 18

摘要

... In terms of structure-based drug design, our knowledge of this chemical series was ... The best compounds resulting from our chemistry effort are summarized in Table 6. Overall, the 10 ... 1 insulin-like growth factor receptor tyrosine kinase and breast cancer: Biology and therapeutic ...