The Journal of Organic Chemistry

Syntheses of. alpha.-chloroketones by reaction of silyl enol ethers with copper (II) chloride and iron (III) chloride

Y Ito, M Nakatsuka, T Saegusa

文献索引：Ito, Yoshihiko; Nakatsuka, Masashi; Saegusa, Takeo Journal of Organic Chemistry, 1980 , vol. 45, p. 2022 - 2024

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被引用次数: 32

摘要

We have already reported a series of reactions of silyl ethers of enols and cyclopropanols with metal salts,'in which metal enolates and metal cyclopropoxides may be assumed as key intermediates. Now we wish to report the reactions of silyl enol ethers with cupric chloride and ferric chloride to produce a-chloro ketones according to eq 1. The reaction provid. es a simple and convenient synthetic method for the preparation of a-chloro ketones under ...