Preparation of (R)-and (S)-N-protected 3-hydroxypyrrolidines by hydroxylation with Sphingomonas sp. HXN-200, a highly active, regio-and stereoselective, and easy …

Z Li, HJ Feiten, D Chang, WA Duetz…

文献索引：Srairi, Driss; Maurey, Georges Bulletin de la Societe Chimique de France, 1987 , # 2 p. 297 - 301

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被引用次数: 64

摘要

... 62% of (S)-15 in 53% ee with an activity of 5.8 U/gCDW (Table 1), significantly better than the hydroxylation with P. putida GPo1 ... in the 13 C NMR spectrum and two signals for OH in the 1 H NMR spectrum were observed, evidencing the existence of two rotamers due ... Scheme 2. ...