Tetrahedron

Oxidative C (Sp 3)–H activation and C–N cleavage of N-methyl amines under transition-metal-free condition for synthesis of methylene-bridged bis-1, 3-diketones

X Wang, Y Wang, Y Yuan, CH Xing

文献索引：Wang, Xiaohu; Wang, Yi; Yuan, Yu; Xing, Chun-Hui Tetrahedron, 2014 , vol. 70, # 12 p. 2195 - 2202

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被引用次数: 7

摘要

Abstract A transition-metal-free oxidative methylenation reaction was developed. Methylene- bridged bis-1, 3-dicarbonyl compounds were synthesized by oxidative C (Sp 3)–H activation and C–N cleavage of N-methyl amines. This novel reaction avoids the use of transition metal catalyst. Furthermore, the reaction are very mild and operational convenient.