Reactivity of 2??Methyl??4H??3, 1??benzoxazin??4??ones and 2??Methyl??4H??pyrido [2, 3??d][1, 3] oxazin??4??one under Microwave Irradiation Conditions

…, A Tzani, N Avlonitis, T Calogeropoulou…

文献索引：Prousis, Kyriakos C.; Tzani, Andromachi; Avlonitis, Nicolaos; Calogeropoulou, Theodora; Detsi, Anastasia Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1313 - 1321

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被引用次数: 3

摘要

Abstract The reactivity of variably substituted 2-methyl-4H-3, 1-benzoxazin-4-ones and 2- methyl-4H-pyrido [2, 3-d][1, 3] oxazin-4-one towards carbon and oxygen nucleophiles under microwave irradiation conditions was investigated. Optimization of the reaction conditions of oxazinones with carbon nucleophiles led to the synthesis of a series of 4-hydroxy-quinolin-2- ones and 4-hydroxy-1, 8-naphthyridin-2-ones in high yields, whereas reaction with a ...