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Journal of Chemical Sciences

Super acid catalysed sequential hydrolysis/cycloisomerization of o-(acetylenic) benzamides under microwave condition: Synthesis, antinociceptive and …

C Praveen, P Dheenkumar, PT Perumal

文献索引:Praveen, Chandrasekaran; Dheenkumar; Perumal Journal of Chemical Sciences, 2013 , vol. 125, # 1 p. 71 - 83

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被引用次数: 6

摘要

Abstract Synthesis of isocoumarins and related compounds via triflic acid promoted hydrolysis/cyclization sequence of 2-(alkynyl) benzamides under microwave condition was achieved. The substrate scope of the reaction was broad to include not only aromatic but also polyaromatic and heteroaromatic motifs, thus highlighting the significance of this methodology. One-pot operation, short reaction time, good chemical yields and excellent ...