Potential Antiradiation Drugs. II. β-Aminomercaptans Derived from D-Allose1, 2

L Goodman, JE Christensen

文献索引：Goodman,L.; Christensen,J.E. Journal of the American Chemical Society, 1961 , vol. 83, p. 3826 - 3827

全文：HTML全文

被引用次数: 16

摘要

A complex neighboring group approach provided a successful synthesis of methyl 3-amino- 2, 3-dideoxy-2-mercapto-a-~-allopyranoside hydrochloride (IX). The blocked 3- aminoaltroside (11) afforded, in two steps, the crystalline dithiocarbamoyl mesylate (VI) which, heated in pyridine, cyclized to the thiazoline V, that was reduced to the thiazolidine 1V. Com-pound IV was deblocked and hydrolyzed, via the crystalline mercuric salt VIII, to ...