前往化源商城

Journal of the American Chemical Society

O 6-(Benzotriazol-1-yl) inosine derivatives: Easily synthesized, reactive nucleosides

S Bae, MK Lakshman

文献索引:Bae, Suyeal; Lakshman, Mahesh K. Journal of the American Chemical Society, 2007 , vol. 129, # 4 p. 782 - 789

全文:HTML全文

被引用次数: 59

摘要

A novel class of O 6-(benzotriazol-1-yl) inosine as well as the corresponding 2'-deoxy derivatives can be conveniently prepared by a reaction between sugar-protected or- unprotected inosine or 2'-deoxyinosine nucleosides and 1 H-benzotriazol-1-yloxy-tris (dimethylamino) phosphonium hexafluorophosphate (BOP). The reaction appears to proceed via a nucleoside phosphonium salt, and in the absence of any additional ...