Novel 2, 3-disubstituted 1, 4-naphthoquinone derivatives and their metal complexes–Synthesis and in vitro cytotoxic effect against mouse fibrosarcoma L929 cells

…, A Salageanu, C Tucureanu, G Marinescu…

文献索引：Niculescu, Violeta-Carolina; Muresan, Nicolae; Salageanu, Aurora; Tucureanu, Catalin; Marinescu, Gabriela; Chirigiu, Liviu; Lepadatu, Costinel Journal of Organometallic Chemistry, 2012 , vol. 700, p. 13 - 19

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被引用次数: 6

摘要

Quinones have various pharmacological properties including antibacterial, antifungal, antiviral, anti-inflammatory, antipyretic and anticancer activity. Two novel 2, 3-disubstituted 1, 4-naphthoquinones and their metal complexes were synthesised, characterized and tested. The cytotoxic potential of the novel 2, 3-disubstituted 1, 4-naphthoquinones and their metal complexes was studied against L929 murine fibroblasts cells grown in vitro. The treatment ...