Synthesis of diverse analogues of Oenostacin and their antibacterial activities

…, A Fatima, JK Kumar, C Chowdhury, HO Saxena…

文献索引：Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.; Khanuja, Suman P.S. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525

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被引用次数: 28

摘要

Several diverse analogues of Oenostacin, a naturally occurring potent antibacterial phenolic acid derivative, have been synthesized. A small library with more than forty analogues having different aromatic rings and varied side chains has been achieved through solution phase synthesis. Some of these analogues, that is, 22, 23 and 42, possessed potent antibacterial activities against Staphylococcus epidermidis and Staphylococcus aureus ...