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Synthesis of potential anticancer agents. XV. Ribonucleosides of 2-substituted purines

HJ Schaeffer, HJ Thomas

文献索引:Schaeffer; Thomas Journal of the American Chemical Society, 1958 , vol. 80, p. 4896,4898

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被引用次数: 19

摘要

A search of the literature revealed that ribosylnucleosides of% substituted purines had not yet been prepared. Because of the potential usefulness that some 2-substituted purine ribonucleosides would have as anticancer agents, we extended our studies to include this important area. Since the value of G-chloro-9-PD-ribofuranosylpurine as an intermediate for the preparation of some G-substi-stuted-9-/?-D-ribofuranosylpurines has been ...