Convenient Synthesis of Substituted Aryl Cyanides and 1, 1-Dicyanobenzyl Benzoate

P Pazdera, J Simbera, M Dlouhy

文献索引：Pazdera, Pavel; Simbera, Jan; Dlouhy, Milan Organic Preparations and Procedures International, 2011 , vol. 43, # 3 p. 285 - 291

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被引用次数: 5

摘要

Various substituted derivatives of benzyl cyanide such as 2, 4-dichlorobenzyl cyanide 2 are important intermediates in the pharmaceutical industry (penicillin derivatives) 1 and for the generation of a number of substances such as herbicides and pesticides. 2–4 Several patents describe methods for the preparation of benzyl cyanides5 and the most frequently used procedure for the preparation of 2, 4-dichlorobenzyl cyanide (2), involving the ...