The parallel asymmetric synthesis of an array of 30 β-amino acids of high enantiomeric purity using the conjugate addition of homochiral lithium N-benzyl-N-(α-methylbenzyl) amide as the key step is accomplished. The experimental simplicity and highly practical nature of the protocol is demonstrated by the efficient parallel conversion of 15 α, β-unsaturated esters to both enantiomeric series of the corresponding β-amino acids in high overall yields and ...
![2-Methyl-2-propanyl (3R)-3-{benzyl[(1S)-1-phenylethyl]amino}-3-ph enylpropanoate结构式](https://image.chemsrc.com/caspic/212/265669-72-5.png)
![tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate结构式](https://image.chemsrc.com/caspic/141/151133-00-5.png)
