Journal of pharmaceutical sciences

Saccharin derivatives IV. Synthesis of 2??(diethylcarbamoyl)??and 2??(diethylthiocarbamoyl) saccharin, and related compounds

SJ Mehta, GH Hamor

文献索引：Mehta,S.J.; Hamor,G.H. Journal of Pharmaceutical Sciences, 1961 , vol. 50, p. 672 - 675

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被引用次数: 3

摘要

Abstract Because acylurea and carbamate groups are associated with various pharmacological activities, a number of saccharin and 6-nitrosaccharin derivatives containing these groups were synthesized for pharmacological screening. The compounds prepared were: 2-(diethylcarbamoyl) saccharin; 2-(diethylcarbamoyl)-6-nitrosaccharin; 2- (diethylthiocarbamoyl) saccharin; and 2-carbethoxysaccharin. Also isolated from the ...