Pursuant to our interest in developing macrolide cyclization techniques which avoid high- dilution requirements, we have investigated the use of a polymer-supported reagent for the preparation of a wide variety of esters. The use of triphenylphosphine and diethyl azodicarboxylate (DEAD) has become well established as a means of formation of esters from alcohols and acids' and of macrolides from precursor w-hydroxy acids. 2 The use of ...
