Phosphonodipeptides: synthesis and separation of diastereoisomers

…, B Lejczak, P Mastalerz, J Szewczyk…

文献索引：Kafarski, Pawel; Lejczak, Barbara; Mastalerz, Przemslaw; Szewczyk, Jerzy; Wasielewski, Czeslaw Canadian Journal of Chemistry, 1982 , vol. 60, p. 3081 - 3084

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被引用次数: 31

摘要

Diastereoisomeric mixtures of phosphonodipeptides, prepared from racemic dialkyl 1- aminoalkanephosphonates, were separated by ion-exchange column chromatography. Phosphonodipeptides were found to be much more readily available from dialkyl 1- aminoalkanephosphonates than from the corresponding free acids and the mixed carboxylic- carbonic anhydride method was found to be the most effective one.