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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Tetrahedron

Enamine Chemistry—XXIV.: Synthesis, thiation, and reduction of lactams

AA El-Barbary, S Carlsson, SO Lawesson

文献索引：El-Barbary, A. A.; Carlsson, S.; Lawesson, S.-O. Tetrahedron, 1982 , vol. 38, # 3 p. 405 - 412

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被引用次数: 20

摘要

Enamines, 1, prepared from cyclohexanones or cyclopentanones are reacted with acrylamide to give lactams, the condensed 2-piperidones, 2. Ethyl 2-(1-pyrrolidinyl)-2- cyclohexene-1-propanoate, 3, when treated with primary amines, produces the corresponding N-substituted 2-piperidones, 4. Ethyl 2-(1-pyrrolidinyl)-2-cyclohexene-1- ethanoates and ethyl 2-(1-pyrrolidinyl)-2-cyclopentene-1-ethanoate, 5, react with primary ...

3,4,4a,5,6,7-hexahydro-2H-cyclopenta[b]pyridine结构式

3,4,4a,5,6,7-he...

乙酸酐结构式

~90%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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1-吡咯烷基-1-环戊烯结构式

1-吡咯烷基-1-环戊烯

~%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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3,4,6,7-TETRAHYDRO-1H-CYCLOPENTA[B]PYRIDIN-2(5H)-ONE结构式

3,4,6,7-TETRAHY...

~%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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1,3,4,5,6,7-hexahydro-2H-cyclopenta[b]pyridine-2-thione结构式

1,3,4,5,6,7-hex...

~%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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3,4,6,7-TETRAHYDRO-1H-CYCLOPENTA[B]PYRIDIN-2(5H)-ONE结构式

3,4,6,7-TETRAHY...

乙酸酐结构式

~%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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乙酸酐结构式

1,3,4,5,6,7-hexahydro-2H-cyclopenta[b]pyridine-2-thione结构式

1,3,4,5,6,7-hex...

~%

1-(2-azabicyclo[4.3.0]non-10-en-2-yl)ethanone结构式

1-(2-azabicyclo...

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2,3,4,4a,5,6,7,8-octahydroquinoline结构式

2,3,4,4a,5,6,7,...

乙酸酐结构式

~92%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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1-(1-吡咯烷)环己烯结构式

1-(1-吡咯烷)环己烯

~%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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3,4,5,6,7,8-六氢喹啉-2(1H)-酮结构式

3,4,5,6,7,8-六氢喹...

~%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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3,4,5,6,7,8-hexahydroquinoline-2(1H)-thione结构式

3,4,5,6,7,8-hex...

~%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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3,4,5,6,7,8-六氢喹啉-2(1H)-酮结构式

3,4,5,6,7,8-六氢喹...

乙酸酐结构式

~%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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乙酸酐结构式

3,4,5,6,7,8-hexahydroquinoline-2(1H)-thione结构式

3,4,5,6,7,8-hex...

~%

Ethanone,1-(3,4,5,6,7,8-hexahydro-1(2H)-quinolinyl)结构式

Ethanone,1-(3,4...

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1-吡咯烷基-1-环戊烯结构式

1-吡咯烷基-1-环戊烯

苄胺结构式

~58%

N-benzylcyclopentanimine结构式

N-benzylcyclope...

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1-(1-吡咯烷)环己烯结构式

1-(1-吡咯烷)环己烯

丙烯酰胺结构式

~%

3,4,5,6,7,8-六氢喹啉-2(1H)-酮结构式

3,4,5,6,7,8-六氢喹...

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3,4,5,6,7,8-六氢喹啉-2(1H)-酮结构式

3,4,5,6,7,8-六氢喹...

~79%

2,3,4,4a,5,6,7,8-octahydroquinoline结构式

2,3,4,4a,5,6,7,...

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3,4,5,6,7,8-hexahydroquinoline-2(1H)-thione结构式

3,4,5,6,7,8-hex...

~87%

2,3,4,4a,5,6,7,8-octahydroquinoline结构式

2,3,4,4a,5,6,7,...

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1-吡咯烷基-1-环戊烯结构式

1-吡咯烷基-1-环戊烯

2-溴-N-苯乙酰胺结构式

2-溴-N-苯乙酰胺

~84%

N-phenyl-2-pyrrolidin-1-ylacetamide结构式

N-phenyl-2-pyrr...

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1-(1-吡咯烷)环己烯结构式

1-(1-吡咯烷)环己烯

2-溴-N-苯乙酰胺结构式

2-溴-N-苯乙酰胺

~82%

N-phenyl-2-pyrrolidin-1-ylacetamide结构式

N-phenyl-2-pyrr...

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Enamine chemistry—XXV: Reduction of enaminones by LiAlH4 and...

[Carlsson, S.; Lawesson, S.-O. Tetrahedron, 1982 , vol. 38, # 3 p. 413 - 417]