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Tetrahedron

Enamine Chemistry—XXIV.: Synthesis, thiation, and reduction of lactams

AA El-Barbary, S Carlsson, SO Lawesson

文献索引：El-Barbary, A. A.; Carlsson, S.; Lawesson, S.-O. Tetrahedron, 1982 , vol. 38, # 3 p. 405 - 412

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被引用次数: 20

摘要

Enamines, 1, prepared from cyclohexanones or cyclopentanones are reacted with acrylamide to give lactams, the condensed 2-piperidones, 2. Ethyl 2-(1-pyrrolidinyl)-2- cyclohexene-1-propanoate, 3, when treated with primary amines, produces the corresponding N-substituted 2-piperidones, 4. Ethyl 2-(1-pyrrolidinyl)-2-cyclohexene-1- ethanoates and ethyl 2-(1-pyrrolidinyl)-2-cyclopentene-1-ethanoate, 5, react with primary ...

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